{"id":2387,"date":"2025-03-14T15:41:31","date_gmt":"2025-03-14T15:41:31","guid":{"rendered":"http:\/\/acto.de.w0211d47.kasserver.com\/projekte\/"},"modified":"2026-01-22T09:16:43","modified_gmt":"2026-01-22T09:16:43","slug":"projects","status":"publish","type":"page","link":"https:\/\/acto.de\/en\/projects\/","title":{"rendered":"Projects"},"content":{"rendered":"\n<p class=\"has-medium-font-size\">The following pages are intended to give you a brief overview of ACTO&#8217;s activities and projects.<\/p>\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\"><div class=\"alignnone\"><style>#sp-ea-1444 .spcollapsing { height: 0; overflow: hidden; transition-property: height;transition-duration: 300ms;}#sp-ea-1444.sp-easy-accordion>.sp-ea-single {margin-bottom: 10px; border: 1px solid #e2e2e2; }#sp-ea-1444.sp-easy-accordion>.sp-ea-single>.ea-header a {color: #444;}#sp-ea-1444.sp-easy-accordion>.sp-ea-single>.sp-collapse>.ea-body {background: #fff; color: #444;}#sp-ea-1444.sp-easy-accordion>.sp-ea-single {background: #eee;}#sp-ea-1444.sp-easy-accordion>.sp-ea-single>.ea-header a .ea-expand-icon { float: left; color: #444;font-size: 16px;}<\/style><div id=\"sp_easy_accordion-1742406364\"><div id=\"sp-ea-1444\" class=\"sp-ea-one sp-easy-accordion\" data-ea-active=\"ea-click\" data-ea-mode=\"vertical\" data-preloader=\"\" data-scroll-active-item=\"\" data-offset-to-scroll=\"0\"><div class=\"ea-card ea-expand sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-14440\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse14440\" aria-controls=\"collapse14440\" href=\"#\" aria-expanded=\"true\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-minus\"><\/i> Ex Vivo Eye Irritation Test (EVEIT)<\/a><\/h3><div class=\"sp-collapse spcollapse collapsed show\" id=\"collapse14440\" data-parent=\"#sp-ea-1444\" role=\"region\" aria-labelledby=\"ea-header-14440\"> <div class=\"ea-body\"><p><strong>Alternatives to Animal Testing<\/strong><\/p><p>The Ex Vivo Eye Irritation Test (EVEIT) offers:<\/p><ul><li>More informative than the non-specific Draize test<\/li><li>Standardized exposures<\/li><li>Reproducible results<\/li><li>Highest analytical precision<\/li><li>Predictive results<\/li><li>Healing and release of inflammatory mediators<\/li><\/ul><p><a href=\"\/en\/projects\/eveit_en\">READ MORE<\/a><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-14441\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse14441\" aria-controls=\"collapse14441\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Burns<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse14441\" data-parent=\"#sp-ea-1444\" role=\"region\" aria-labelledby=\"ea-header-14441\"> <div class=\"ea-body\"><h3 class=\"orange \"><strong><small class=\"orange\">Developing New Therapies<\/small><\/strong><\/h3><p>The eye clinics at RWTH Aachen University and in Cologne-Merheim can draw on a wealth of clinical experience in the acute care of chemical burns, as well as in subsequent therapy. This experience forms the basis for developing long-term research concepts.<\/p><p><a href=\"\/en\/projects\/acid-burns\/\">READ MORE<\/a><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-14442\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse14442\" aria-controls=\"collapse14442\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> High-Speed-Camera<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse14442\" data-parent=\"#sp-ea-1444\" role=\"region\" aria-labelledby=\"ea-header-14442\"> <div class=\"ea-body\"><h3 class=\"orange\"><strong><small class=\"orange\">Seeing what otherwise remains invisible&#8230;<\/small><\/strong><\/h3><p>ACTO&#8217;s laboratory equipment has been expanded with a high-speed video camera (Optronis CR3000x2) to optimally document processes at biological interfaces over time.<\/p><p>A sensor resolution of 1,696 x 1,710 pixels ensures highly precise imaging.<\/p><p>The camera can record videos at up to 100,000 frames per second, making even the fastest processes visible.<\/p><p>The recordings can also be further refined using specialized analysis software.<\/p><p><a href=\"\/en\/projects\/high-speed-camera\/\">READ MORE<\/a><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-14443\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse14443\" aria-controls=\"collapse14443\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> SARS-Cov2<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse14443\" data-parent=\"#sp-ea-1444\" role=\"region\" aria-labelledby=\"ea-header-14443\"> <div class=\"ea-body\"><h3><strong>Vaccination via the Eye<\/strong><\/h3><p>Since infection with SARS-CoV-2 occurs via the mucous membranes and replication primarily takes place there, immunization should begin or be enhanced in this area. The site of initial viral contact plays a crucial role in an optimal immune response.<\/p><p>So why not use an existing vaccine and administer it, highly diluted, into the conjunctival sac of the eye? If this is where the initial contact with the virus occurs, a corresponding immune response, including the production of IgA, should be detectable, ultimately leading to sterility.<\/p><p><a href=\"\/en\/projects\/vaccination-epiconjunctival\">READ MORE<\/a><\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\"><\/div>\n<\/div>\n\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-829b1d53 wp-block-columns-is-layout-flex\" style=\"margin-bottom:0\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The following pages are intended to give you a brief overview of ACTO&#8217;s activities and projects.<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2387","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/acto.de\/en\/wp-json\/wp\/v2\/pages\/2387","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/acto.de\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/acto.de\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/acto.de\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/acto.de\/en\/wp-json\/wp\/v2\/comments?post=2387"}],"version-history":[{"count":3,"href":"https:\/\/acto.de\/en\/wp-json\/wp\/v2\/pages\/2387\/revisions"}],"predecessor-version":[{"id":2396,"href":"https:\/\/acto.de\/en\/wp-json\/wp\/v2\/pages\/2387\/revisions\/2396"}],"wp:attachment":[{"href":"https:\/\/acto.de\/en\/wp-json\/wp\/v2\/media?parent=2387"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}